New Frontiers: Neuroinflammation
2025–2026 studies using advanced PET imaging have confirmed microglial activation (inflammation in the brain) in fibromyalgia patients.
The Autoimmune Theory
Groundbreaking research showed that transferring antibodies (IgG) from fibromyalgia patients into mice induced pain hypersensitivity. This suggests that for some patients, the immune system may be directly driving the condition.
Biomarker Progress
While not yet a standard blood test, these discoveries point toward objective diagnostics moving away from "diagnosis by exclusion."