Patient Guideline (2025 Edition)

Patient Version of Guideline (2025)

A new international multidisciplinary guideline, published in the Journal of Evidence-Based Medicine, bridges the gap between science and daily management.

Core Recommendations

• Multimodal Care: The most effective treatment combines education, exercise, and (if needed) medication.
• Non-Drug First: Management should always begin with non-pharmacological interventions like aerobic exercise and CBT.
• Mind-Body Evidence: Strong support for Tai Chi and Yoga as primary interventions for pain and mood.

The guideline emphasizes that pain is nociplastic — a biological dysfunction of the nervous system, not imaginary.